{"id":43720,"date":"2024-04-09T10:50:36","date_gmt":"2024-04-09T07:50:36","guid":{"rendered":"https:\/\/mu-sofia.bg\/international-activities\/bnrrp\/research-groups\/dementia-research-group-for-early-diagnosis-and-prevention\/"},"modified":"2024-04-09T10:51:02","modified_gmt":"2024-04-09T07:51:02","slug":"dementia-research-group-for-early-diagnosis-and-prevention","status":"publish","type":"page","link":"https:\/\/mu-sofia.bg\/en\/international-activities\/bnrrp\/research-groups\/dementia-research-group-for-early-diagnosis-and-prevention\/","title":{"rendered":"Dementia research group for early diagnosis and prevention"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"43720\" class=\"elementor elementor-43720 elementor-43226\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-aa902d8 elementor-section-stretched elementor-section-full_width 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UNIVERSITY<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af197fe elementor-nav-menu__align-center elementor-nav-menu--dropdown-mobile elementor-nav-menu__text-align-aside elementor-nav-menu--toggle elementor-nav-menu--burger elementor-widget elementor-widget-nav-menu\" data-id=\"af197fe\" data-element_type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;horizontal&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;i class=\\&quot;fas fa-caret-down\\&quot; aria-hidden=\\&quot;true\\&quot;&gt;&lt;\\\/i&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;},&quot;toggle&quot;:&quot;burger&quot;}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"Menu\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-horizontal e--pointer-underline e--animation-fade\">\n\t\t\t\t<ul id=\"menu-1-af197fe\" class=\"elementor-nav-menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42640\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/za-proekta\/\" class=\"elementor-item\">About<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42821\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/nauchni-grupi\/\" class=\"elementor-item\">Research groups<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42830\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/kontakti\/\" class=\"elementor-item\">Contacts<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t<div class=\"elementor-menu-toggle\" role=\"button\" tabindex=\"0\" aria-label=\"Menu Toggle\" aria-expanded=\"false\">\n\t\t\t<i aria-hidden=\"true\" role=\"presentation\" class=\"elementor-menu-toggle__icon--open eicon-menu-bar\"><\/i><i aria-hidden=\"true\" role=\"presentation\" class=\"elementor-menu-toggle__icon--close eicon-close\"><\/i>\t\t<\/div>\n\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-af197fe\" class=\"elementor-nav-menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42640\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/za-proekta\/\" class=\"elementor-item\" tabindex=\"-1\">About<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42821\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/nauchni-grupi\/\" class=\"elementor-item\" tabindex=\"-1\">Research groups<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42830\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/kontakti\/\" class=\"elementor-item\" tabindex=\"-1\">Contacts<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-63232a7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"63232a7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-aa22b67\" data-id=\"aa22b67\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-29cb29c elementor-widget elementor-widget-heading\" data-id=\"29cb29c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">research group<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d914d1 elementor-widget elementor-widget-heading\" data-id=\"0d914d1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dementia research group for early diagnosis and prevention<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ce11606 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ce11606\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7be0e08\" data-id=\"7be0e08\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cae948f elementor-widget elementor-widget-heading\" data-id=\"cae948f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Main research area of the group<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-68f245b elementor-widget elementor-widget-text-editor\" data-id=\"68f245b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>dementia, cognitive impairment, neuropsychology, genetics, biomarkers, neuroimaging, early diagnosis, prevention<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5c9125f elementor-widget elementor-widget-heading\" data-id=\"5c9125f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Leading researcher:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3b11081 elementor-widget elementor-widget-text-editor\" data-id=\"3b11081\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Acad. Prof. Latchezar Traykov, MD, PhD, DSc<\/strong><\/p>\n<p>Medical Faculty, Department of Neurology, MU \u2013 Sofia<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-bf74bfb\" data-id=\"bf74bfb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-16025d2 elementor-widget elementor-widget-heading\" data-id=\"16025d2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Members of the research team:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-946d3e7 elementor-widget elementor-widget-text-editor\" data-id=\"946d3e7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n<li>Assoc. Prof., MD, PhD, DSc, Shima Mehrabian-Spassova;<\/li>\n<li>Assoc. prof. Margarita Raycheva;<\/li>\n<li>Assoc. Prof., MD, PhD, Mariya Ivanova Petrova;<\/li>\n<li>Assist. Prof. MD, PhD, Sylvia Petrova Skelina;<\/li>\n<li>Assist. {Prof. MD, PhD, Yavor Zhelev;<\/li>\n<li>Assist. Prof. MD, Hristo Krushkov;<\/li>\n<li>MD, PhD, Zdravka Zheleva;<\/li>\n<li>Prof., MD, PhD, Georgi Onchev;<\/li>\n<li>MD, PhD, Desislava Ignatova;<\/li>\n<li>MD, Irena Dreharova-Kireva;<\/li>\n<li>MD, Diyana Belezhanska-Odzhakova;<\/li>\n<li>Prof. MD, PhD, DSc, Dora Zlatareva;<\/li>\n<li>Assist. prof., MD, PhD, Nevena Fileva;<\/li>\n<li>Assoc. prof., MD, PhD, Valeriq Hadzhiyska-Popova<\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-db706d5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"db706d5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5405223\" data-id=\"5405223\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dfa8b6a elementor-widget elementor-widget-heading\" data-id=\"dfa8b6a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Research goals<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6fc70fc elementor-widget elementor-widget-text-editor\" data-id=\"6fc70fc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The main objective of this study is to apply a multidisciplinary approach with identification and follow-up of a group of patients with predementia states of neurodegenerative disorders and to identify sensitive clinical, neuropsychological, neuropsychiatric, biochemical (blood and<br \/>\ncerebrospinal fluid), modifiable risk factors and neuroimaging biomarkers for implementation of a multimodal preventive intervention.<\/p>\n<p>This study sets the following secondary objectives:<br \/>\n1. Creation of a specific package of blood, cerebrospinal fluid, neuropsychological,neuropsychiatric and neuroimaging markers for characterization and follow-up of patients with pre-dementia states of neurodegenerative disorders for prediction of conversion to dementia<br \/>\nand screening for markers that can distinguish the state from normal controls.<br \/>\n2. Establishment of the sequence of occurrence of the deficit in different cognitive areas in subjects with SCI, MCI and\/or MBI.<br \/>\n3. Determining the role and profile of blood and cerebrospinal fluid biomarkers for assessing the predementia states of neurodegenerative disorders and prediction of possible dementia progression as well as the type of dementia.<br \/>\n4. Determining the role of neuropsychological and neuropsychiatric markers for assessing the pre-dementia states of neurodegenerative disorders and prediction of possible dementia progression as well as the type of dementia.<br \/>\n5. Determining the role of neuroimaging markers for assessment of pre-dementia states of neurodegenerative disorders and prediction of possible dementia progression as well as the type of dementia.<br \/>\n6. Determining the association of MBI with amyloid and\/or tau pathology, and<br \/>\nneurodegeneration.<br \/>\n7. Determining of dementia conversion rate and type in a longitudinal follow-up of the subjects with SCI, MCI, and\/or MBI<br \/>\n8. Investigation the effect of multimodal preventive intervention in a group of subjects with SCI, MCI, and\/or MBI with different biomarker profile.<br \/>\n9. Biobanking.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2bd2f13\" data-id=\"2bd2f13\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RESEARCH UNIVERSITY research group Dementia research group for early diagnosis and prevention Main research area of the group dementia, cognitive impairment, neuropsychology, genetics, biomarkers, neuroimaging, early diagnosis, prevention Leading researcher: Acad. Prof. Latchezar Traykov, MD, PhD, DSc Medical Faculty, Department of Neurology, MU \u2013 Sofia Members of the research team: Assoc. Prof., MD, PhD, DSc, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":43641,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-43720","page","type-page","status-publish","hentry","wpbf-post"],"_links":{"self":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages\/43720","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/comments?post=43720"}],"version-history":[{"count":0,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages\/43720\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages\/43641"}],"wp:attachment":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/media?parent=43720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}