{"id":43776,"date":"2024-04-09T11:25:03","date_gmt":"2024-04-09T08:25:03","guid":{"rendered":"https:\/\/mu-sofia.bg\/international-activities\/bnrrp\/research-groups\/vascage-bg\/"},"modified":"2024-04-09T11:25:30","modified_gmt":"2024-04-09T08:25:30","slug":"vascage-bg","status":"publish","type":"page","link":"https:\/\/mu-sofia.bg\/en\/international-activities\/bnrrp\/research-groups\/vascage-bg\/","title":{"rendered":"VascAge BG"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"43776\" class=\"elementor elementor-43776 elementor-43302\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-438ed39 elementor-section-stretched elementor-section-full_width elementor-section-height-min-height elementor-section-height-default elementor-section-items-middle\" data-id=\"438ed39\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d5fcbc6\" data-id=\"d5fcbc6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-203c7f6 elementor-widget elementor-widget-heading\" data-id=\"203c7f6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">RESEARCH UNIVERSITY<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3791f58 elementor-nav-menu__align-center elementor-nav-menu--dropdown-mobile 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class=\"elementor-item\">About<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42821\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/nauchni-grupi\/\" class=\"elementor-item\">Research groups<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42830\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/kontakti\/\" class=\"elementor-item\">Contacts<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t<div class=\"elementor-menu-toggle\" role=\"button\" tabindex=\"0\" aria-label=\"Menu Toggle\" aria-expanded=\"false\">\n\t\t\t<i aria-hidden=\"true\" role=\"presentation\" class=\"elementor-menu-toggle__icon--open eicon-menu-bar\"><\/i><i aria-hidden=\"true\" role=\"presentation\" class=\"elementor-menu-toggle__icon--close eicon-close\"><\/i>\t\t<\/div>\n\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-3791f58\" class=\"elementor-nav-menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42640\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/za-proekta\/\" class=\"elementor-item\" tabindex=\"-1\">About<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42821\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/nauchni-grupi\/\" class=\"elementor-item\" tabindex=\"-1\">Research groups<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42830\"><a href=\"https:\/\/mu-sofia.bg\/mezhdunarodna-dejnost\/npvu\/kontakti\/\" class=\"elementor-item\" tabindex=\"-1\">Contacts<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c31d637 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c31d637\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d22930b\" data-id=\"d22930b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ba51db5 elementor-widget elementor-widget-heading\" data-id=\"ba51db5\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">research group<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-919debf elementor-widget elementor-widget-heading\" data-id=\"919debf\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">VascAge BG<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2ecb00d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2ecb00d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-a09feeb\" data-id=\"a09feeb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b543167 elementor-widget elementor-widget-heading\" data-id=\"b543167\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Main research area of the group<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b57e894 elementor-widget elementor-widget-text-editor\" data-id=\"b57e894\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Research in the field of molecular and personalized medicine<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a5a40b4 elementor-widget elementor-widget-heading\" data-id=\"a5a40b4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Leading researchers<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c87637b elementor-widget elementor-widget-text-editor\" data-id=\"c87637b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Prof. Arman Postadzhiyan, MD, PhD, FESC, FACC<\/strong><\/p>\n<p>Medical faculty, department Family Medicine, MU \u2013 Sofia; University Hospital Saint Anna, Sofia, Bulgaria, Deparment Cardiology<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-f0422d3\" data-id=\"f0422d3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-424672f elementor-widget elementor-widget-heading\" data-id=\"424672f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Members of the research team:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2fcb5e7 elementor-widget elementor-widget-text-editor\" data-id=\"2fcb5e7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Assoc. Prof. Vasil Velchev, MD, PhD, FESC; Reni Tzveova,<br \/>\nPhD; Prof. Margarita D. Apostolova, Ph.D; Prof. Dobroslav Kyurkchiev, MD, PhD, DSci<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6dc2f40 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6dc2f40\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-627dae9\" data-id=\"627dae9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-31092e7 elementor-widget elementor-widget-heading\" data-id=\"31092e7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Research goals<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-59569a1 elementor-widget elementor-widget-text-editor\" data-id=\"59569a1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tThe research objective of the proposed program is to identify and clinically validate biomarkers\r\nof vascular aging as potential prognostic and therapeutic modalities in patients at risk or with\r\nadvanced cardiovascular disease.\r\nTo achieve the main objective described the following specific tasks shall be accomplished by\r\nVASCAge BG research group\r\n&#8211; Harmonizing knowledge about vascular aging and methods for assessing pulse wave\r\ndynamics by initiating a registry for clinical validation of the most established methodologies\r\n(different methods for studying pulse wave velocity, central aortic pressure, wave separation\r\nanalysis), including a comparison of invasive and non-invasive techniques\r\n&#8211; Construction of a data set among individuals without obvious cardiovascular disease to\r\nidentify Bulgarian norms for normal and early vascular aging by using non-invasive\r\nmethods. Search and association of selected pulse wave biomarkers with classical risk\r\nfactors, components of metabolic syndrome and imaging methods for atherosclerotic\r\ninvolvement of coronary, carotid, femoral segments and abdominal aorta\r\n&#8211; Assessment of the presence and severity of heart failure with preserved ejection fraction\r\namong patients with early vascular aging\r\n&#8211; Assessment of the diagnostic and prognostic performance of markers of early vascular\r\naging \u2013 augmentation index, reflection magnitude, central BP among patients with heart\r\nfailure with preserved ejection fraction at different level of risk \u2013 with or without pulmonary\r\nhypertension\r\n&#8211; Molecular-biological, genetic and clinical-instrumental phenotyping of heart failure with\r\npreserved ejection fraction and search for a relationship with the clinical course of the\r\ndiseases\r\n&#8211; Define innovative big data approaches for the identification of vascular aging risk factors to\r\nbe employed for the implementation of prevention and screening programs\r\nThe successful realization of the program will enable the formation of an interdisciplinary expert\r\nhub and research center for evidence-based early disease risk assessment and personalized\r\napproach in cardiovascular diseases\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-c735075\" data-id=\"c735075\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RESEARCH UNIVERSITY research group VascAge BG Main research area of the group Research in the field of molecular and personalized medicine Leading researchers Prof. Arman Postadzhiyan, MD, PhD, FESC, FACC Medical faculty, department Family Medicine, MU \u2013 Sofia; University Hospital Saint Anna, Sofia, Bulgaria, Deparment Cardiology Members of the research team: Assoc. Prof. Vasil Velchev, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":43641,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-43776","page","type-page","status-publish","hentry","wpbf-post"],"_links":{"self":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages\/43776","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/comments?post=43776"}],"version-history":[{"count":0,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages\/43776\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/pages\/43641"}],"wp:attachment":[{"href":"https:\/\/mu-sofia.bg\/en\/wp-json\/wp\/v2\/media?parent=43776"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}